N,N-Dibutyl-4-nitroaniline → HCID 11680158, compound

HRID 1243150Notes

Reaction equation

HRID 1243150 reaction equation
[N+:1]([C:4]1[CH:18]=[CH:17][C:7]([N:8]([CH2:13][CH2:14][CH2:15][CH3:16])[CH2:9][CH2:10][CH2:11][CH3:12])=[CH:6][CH:5]=1)([O-])=O>CO.[Pd]>[CH2:9]([N:8]([CH2:13][CH2:14][CH2:15][CH3:16])[C:7]1[CH:6]=[CH:5][C:4]([NH2:1])=[CH:18][CH:17]=1)[CH2:10][CH2:11][CH3:12]

Participants

4

Reactant 1

HCID 13795418N,N-Dibutyl-4-nitroaniline

Product 1

HCID 11680158HCID 11680158, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of 4-nitro-N,N-dibutylaniline from Example 40A (1.0 g, 4.0 mmol) in methanol (10 ml) was added palladium 10 wt % on activated carbon (85 mg, 0.08 mmol) under an atmosphere of hydrogen. The reaction mixture was stirred at room temperature for 4 hours and filtered through celite. After solvent were removed under reduced pressure, the titled material was obtained as a white solid, which was used in next step without purification.

Workup

  1. filtrationfiltered through celite
  2. customAfter solvent were removed under reduced pressure

Sources & evidence

ORD record
ord-85d189a85359411399ed03b60f7a19f3
Source dataset
uspto-grants-2006_10
Patent number
US07115767B2

Reaction notes

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