反应详情

A solution of 4-dodecyloxybenzaldehyde (37.12 g, 0.128 mol), 2-aminobenzenethiol (16 g, 0.128 mol) and dimethylsulfoxide acid (200 cm3) was heated under reflux for 24 hours. The cooled solution was added to water and extracted into dichloromethane (3×50 cm3). The combined organic layers were dried (MgSO4), filtered and the filtrate evaporated down under reduced pressure. The solid residue was recrystallised from ethanol to give 23.1 g (45.7%) of the desired product.

1. temperatureunder reflux for 24 hours
2. extractionextracted into dichloromethane (3×50 cm3)
3. dry with materialThe combined organic layers were dried (MgSO4)
4. filtrationfiltered
5. customthe filtrate evaporated down under reduced pressure
6. customThe solid residue was recrystallised from ethanol