3-Pyridinecarboxaldehyde → Hydrochloric Acid

Participants

Reaction Steps

2-chloro-10-(1-pyridin-3-yl-methylpiperidin-3-yl)-10H-phenothiazine was prepared by treatment of 2-chloro-10-piperidin-3-yl-10H-phenothiazine (240 mg, 0.757 mmol) and 3-pyridinecarboxaldehyde (81 mg, 0.757 mmol) with sodium triacetoxyborohydride (224 mg, 1.06 mmol) to provide after treatment with ethereal HCl, the sub-titled compound (136 mg, 41%).

Provenance & Evidence