Cyclopentane-1,1-diacetic anhydride → HCID 10207073, compound

Participants

Role	Name	HCID	Charge
Reactant	Cyclopentane-1,1-diacetic anhydride	HCID 79743	—
Reactant	N'-hydroxy-3-(2-methyl-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanimidamide	HCID 21927822	—
Solvent	1,4-Dioxane	HCID 31275	—
Product	HCID 10207073	HCID 10207073	—

Reaction Conditions

Temperature	100 °C

Reaction Steps

A stirred mixture of the product of EXAMPLE 7, STEP 3 (100 mg), 3,3-tetramethyleneglutaric anhydride (80 mg, Aldrich) and 1,4-dioxane (2 mL, Aldrich) was heated to 100° C. for 16 hrs. The resulting mixture was purified by HPLC to provide the title compound as a gum. 1H (CD3OD) δ 1.66 (8H, m); (1.93, 2H, p); 2.40 (3H, s); 2.42 (2H, s); 2.77 (2H, t); 2.97 (2H, t); 3.00 (2H, t); 3.14 (2H, s); 3.46 (2H, t); 7.51 (1H, s).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07119098B2
Source dataset	uspto-grants-2006_10
ORD ID	ord-97cd7c0f3d50446d8114f8dad6ac5dca
Source note	uspto-grants-2006_10