HCID 21927829, compound → HCID 86585917, compound

Participants

Reaction Steps

Prepared in an analogous manner to 4-[4-(N-pyridin-2-yl-beta-alanyl)-piperazin-1-yl]butanoic acid bis(trifluoroacetate) using methyl 4-(4-{3-[(tertbutoxycarbonyl)amino]propyl}piperazin-1-yl)butanoate in the place of methyl 4-{4-[N-(tert-butoxycarbonyl)-beta-alanyl]piperazin-1-yl}butanoate. 1H NMR (400 MHz, CD3CN) δ 7.91 (dt, 1 H), 7.82 (d, 1 H), 6.97 (d, 1 H), 6.86 (m, 1H), 3.60–3.42 (m, 8 H), 3.19–3.03 (m, 6 H), 2.44 (t, 2 H), 2.08 (t, 2 H), 1.95 (d, 2 H); MS (ESI+) for m/z 307 (M+H)+.

Provenance & Evidence