反应详情

A solution of the amine from example 4 (300 mg, 0.79 mmol) in formic acid (15 ml) was stirred at 80° C. for 3 hours. The cooled mixture was concentrated under reduced pressure and the residue was partitioned between ethyl acetate and sodium bicarbonate solution. The layers were separated, and the organic phase was evaporated under reduced pressure to give the title compound.

1. concentrationThe cooled mixture was concentrated under reduced pressure
2. customthe residue was partitioned between ethyl acetate and sodium bicarbonate solution
3. customThe layers were separated
4. customthe organic phase was evaporated under reduced pressure