Methanol → methyl 6,6-diphenyl-6,7-dihydro-2H-indazole-3-carboxylate

HRID 1243822Notes

Reaction equation

HRID 1243822 reaction equation
[C:1]1([C:7]2([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:15][C:14]3[NH:13][N:12]=[C:11]([C:16]([OH:18])=[O:17])[C:10]=3[CH:9]=[CH:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:25]O>>[C:19]1([C:7]2([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[CH2:15][C:14]3[C:10](=[C:11]([C:16]([O:18][CH3:25])=[O:17])[NH:12][N:13]=3)[CH:9]=[CH:8]2)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 887MethanolHCID 219286736,6-diphenyl-6,7-dihydro-1H-indazole-3-carboxylic acid

Product 1

HCID 178499155methyl 6,6-diphenyl-6,7-dihydro-2H-indazole-3-carboxylate

Procedure

56 mg of 6,6-diphenyl-6,7-dihydro-1H-indazole-3-carboxylic acid and 10 cm3 of methanol are treated as in Example 2-1 to give 39 mg of methyl 6,6-diphenyl-6,7-dihydro-2H-indazole-3-carboxylate, in the form of a white foam, the characteristics of which are as follows:

Sources & evidence

ORD record
ord-d13d7b9de8134983ab28352838beaab2
Source dataset
uspto-grants-2006_10
Patent number
US07119115B2

Reaction notes

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