HCID 21931038, compound → HCID 21931051, compound

HRID 1243974Notes

Reaction equation

HRID 1243974 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[CH:11][C:10]([C:13]3[CH:26]=[CH:25][C:16]([O:17][C:18]4[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][CH:19]=4)=[CH:15][CH:14]=3)=[N:9]2)=[CH:4][CH:3]=1.Br[C:28]1(CCOCC)C(=O)NC(=O)NC1=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH:12]=[CH:11][C:10]([C:13]3[CH:26]=[CH:25][C:16]([O:17][C:18]4[CH:23]=[CH:22][C:21]([O:24][CH3:28])=[CH:20][CH:19]=4)=[CH:15][CH:14]=3)=[N:9]2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 21931038HCID 21931038, compoundHCID 219311235-Bromo-5-(2-ethoxy-ethyl)-pyrimidine-2,4,6-trione

Product 1

HCID 21931051HCID 21931051, compound

Procedure

By the same procedure as Example 1, Part C, 4-{4-[1-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-phenoxy}-phenol and 5-bromo-5-(2-methoxyethyl)-pyrimidine-2,4,6-trione (from Preparation 3B) were converted to the title compound. MS m/z: ESI+ 547.1 (M+H)+, ESI− 545.3 (M−H)−.

Sources & evidence

ORD record
ord-fce0dd158ba34f2cb6aa61f44baad1a4
Source dataset
uspto-grants-2006_10
Patent number
US07119201B2

Reaction notes

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