反应详情

Example 241 was prepared using the same procedure as described for Example 240 substituting 2-(2-cyano-acetylamino)-4-phenylethynyl-thiophene-3-carboxylic acid ethyl ester (0.087 g, 0.256 mmol) for 2-(2-Cyano-acetylamino)-4-styryl-thiophene-3-carboxylic acid ethyl ester in Example 240 to give the title compound (0.0043 g, 5.8%). MS m/e (CI) 292.8 (M+H)+314.8 (M+Na); 1H NMR (300 MHz, MeOH-d4) δ ppm 7.09 (s, 1H), 7.33 (m, 3H), 7.58 (m, 2H).

1. customExample 241 was prepared