反应详情

The salt is prepared by adding silver nitrate (0.50 g, 2.96 mmoles) to a solution of Dextrorphan hydrobromide (1 g, 2.96 mmoles) in acetonitrile (17 ml). The solution is then stirred at room temperature for 30 minutes. Filtering is then effected to remove silver bromide precipitate. The clear solution is added of ethyl ether (100 ml). A precipitate is formed, that is filtered, washed with ethyl ether and dried under vacuum. The solid obtained at the elemental analysis corresponds to the nitrate salt of Dextrorphan:

1. customThe salt is prepared
2. filtrationFiltering
3. customto remove silver bromide precipitate
4. additionThe clear solution is added of ethyl ether (100 ml)
5. customA precipitate is formed
6. filtrationthat is filtered
7. washwashed with ethyl ether
8. customdried under vacuum