HCID 58613354, compound → HCID 58613358, compound

Participants

Reaction Steps

A solution of the Boc-protected amine D7 (1.05 g, 0.00199 moles) in 1.4-dioxane (20 ml) and 4M HCl in dioxane (10 ml) was stirred under argon at room temperature overnight. The resultant mixture was evaporated to dryness to give the hydrochloride salt of the title compound D9 as a cream solid (0.96 g, 100%). M-H 448.5. 1H NMR: δ DMSO-d6 3.08 (4H, m), 3.32 (4H, br s), 3.52 (3H, s), 6.85 (1H, s), 7.10 (1H, s), 7.41 (1H, d), 7.49–7.53 (3H, m), 7.69 (1H, s), 7.73 (1H, s), 9.27 (2H,br s), 9.74 (1 H, br s).

Provenance & Evidence