2,6-Dichloropyrazine → HCID 21919341, compound

HRID 1244404Notes

Reaction equation

HRID 1244404 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:11][CH3:12])[CH:10]=1)[CH2:6][NH2:7].[Cl:13][C:14]1[CH:19]=[N:18][CH:17]=[C:16](Cl)[N:15]=1>>[Cl:13][C:14]1[N:15]=[C:16]([NH:7][CH2:6][C:5]2[CH:8]=[C:9]([O:11][CH3:12])[CH:10]=[C:3]([O:2][CH3:1])[CH:4]=2)[CH:17]=[N:18][CH:19]=1

Participants

3

Reactant 2

HCID 785042,6-DichloropyrazineHCID 420973(3,5-Dimethoxyphenyl)methanamine

Product 1

HCID 21919341HCID 21919341, compoundYield 91%

Procedure

In a procedure analogous to Example 21, reaction of 3,5-dimethoxybenzylamine and 2,6-dichloropyrazine furnished the product (91%).

Sources & evidence

ORD record
ord-afc15629a810416a8f05c17cdb3409aa
Source dataset
uspto-grants-2006_10
Patent number
US07122550B2

Reaction notes

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