Ether, ethyl ethynyl → HCID 21919772, compound

Participants

Reaction Steps

Was prepared from 4-methoxy cyclohexanecarbonyl chloride (10 g, 52.1 mmol) and ethoxyacetylene (7.5 g, 0.10 mol) according to the method of Intermediate 1 to give the title compound as an approx. 1:1 mixture of isomers, as a pale yellow oil (7.2 g, 34.4 mmol, 65%). δH (CDCl3, 300K) 4.81–4.79 (1H, s), 4.22–4.20 (2H q, J 7.1 Hz), 3.34–3.32 (3H, s), 3.31–3.22 (1H, m), 2.04–1.56 (8H, m), 1.44–1.43 (3H t, J 7.1 Hz); m/z (ES+, 70V) 211.0 (MH+).

Provenance & Evidence