HuagongsheHuagongshe Chemistry Print Report · For research reference only
Itaconic acid → HCID 21920039, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Itaconic acid | HCID 811 | — |
| Reactant | 4-[2-(4-Fluorophenyl)ethenyl]aniline | HCID 6444569 | — |
| Product | HCID 21920039 | HCID 21920039 | — |
Reaction Steps
In an analogous manner to that described in Example 36 c), the reaction of (E)-4-[2-(4-fluoro-phenyl)-vinyl]-phenylamine with itaconic acid yields the (RS)-(E)-1-{4-[2-(4-fluoro-phenyl)-vinyl]-phenyl}-5-oxo-pyrrolidine-3-carboxylic acid which was directly engaged in the next step without further purification and characterisation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07122562B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-4985a3cd539040c88ae5d1bd8eb551bb |
| Source note | uspto-grants-2006_10 |