2-Oxo-2-(thiophen-2-yl)acetaldehyde → 4-(7-Thiophen-2-yl-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-ylmethyl)-phenol

Participants

Reaction Steps

General procedure A was followed with the reaction of oxo-thiophen-2-yl-acetaldehyde and 4-(4,5-diamino-4H-[1,2,4]triazol-3-ylmethyl)-phenol to provide 4-(7-thiophen-2-yl-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-ylmethyl)-phenol and the desired product 4-(6-thiophen-2 -yl[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-ylmethyl)-phenol (example 2).

Provenance & Evidence