HCID 1268221, compound → 285996-74-9

HRID 1244671Notes

Reaction equation

HRID 1244671 reaction equation
[CH:1]1[C:13]2[CH:12]([CH2:14][O:15][C:16]([NH:18][C:19]3([C:29]([OH:31])=[O:30])[CH2:28][CH2:27][C:22]4(OCC[O:23]4)[CH2:21][CH2:20]3)=[O:17])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1>CC(C)=O>[CH:1]1[C:13]2[CH:12]([CH2:14][O:15][C:16]([NH:18][C:19]3([C:29]([OH:31])=[O:30])[CH2:20][CH2:21][C:22](=[O:23])[CH2:27][CH2:28]3)=[O:17])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 1

HCID 1268221HCID 1268221, compound

Product 1

HCID 1268238285996-74-9

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

187 mmol (79 g) of 8-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1,4-dioxaspiro[4,5]decane-8-carboxylic acid is taken up in 3.51 of acetone/0.1 M HCl 1:1 and stirred for 4 hours at room temperature. The acetone is drawn off in a rotary evaporator, and the precipitated product is filtered off, rewashed with water and dried. Yield: 68.7 g of 2.

Workup

  1. customThe acetone is drawn off in a rotary evaporator
  2. filtrationthe precipitated product is filtered off
  3. customdried

Sources & evidence

ORD record
ord-aaac8efa1a764629999d2b22682c26f6
Source dataset
uspto-grants-2006_10
Patent number
US07122570B2

Reaction notes

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