(2,4-Dichlorophenyl)hydrazine → HCID 10173283, compound

HRID 1244678Notes

Reaction equation

HRID 1244678 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[C:12](=[C:13](Cl)[CH:14]=1)[NH:11][C:10]1[CH2:9][CH2:8][C:7]([CH2:25][CH2:26][CH2:27][C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)([C:16]([NH:18][C@H:19]([CH2:23][OH:24])[CH:20]([CH3:22])[CH3:21])=[O:17])[CH2:6][C:5]2=1.ClC1C=C(Cl)C=CC=1NN>>[OH:24][CH2:23][C@@H:19]([NH:18][C:16]([C:7]1([CH2:25][CH2:26][CH2:27][C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:6][C:5]2[C:4]3[C:12](=[CH:13][CH:14]=[CH:2][CH:3]=3)[NH:11][C:10]=2[CH2:9][CH2:8]1)=[O:17])[CH:20]([CH3:22])[CH3:21]

Participants

3

Reactant 2

HCID 408929(2,4-Dichlorophenyl)hydrazineHCID 69595590HCID 69595590, compound

Product 1

HCID 10173283HCID 10173283, compound

Procedure

25 mg of 6,8-dichloro-2,3,4,9-tetrahydro-N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-3-(3-phenylpropyl)-1H-carbazole-3-carboxamide 278 is produced analogously with use of 2,4-dichlorophenylhydrazine.

Sources & evidence

ORD record
ord-e56a0edcc224401c9ecd878e42588809
Source dataset
uspto-grants-2006_10
Patent number
US07122570B2

Reaction notes

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