(2,4-Dichlorophenyl)hydrazine → HCID 10287594, compound
Reaction equation
Cl[C:2]1[CH:3]=[C:4]2[C:12](=[C:13](Cl)[CH:14]=1)[NH:11][C:10]1[CH2:9][CH2:8][C:7]([CH2:25][NH:26][C@@H:27]([CH:30]([CH3:32])[CH3:31])[CH2:28][OH:29])([CH2:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:6][C:5]2=1.ClC1C=C(Cl)C=CC=1NN>>[CH3:31][CH:30]([CH3:32])[C@H:27]([NH:26][CH2:25][C:7]1([CH2:16][CH2:17][CH2:18][C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:6][C:5]2[C:4]3[C:12](=[CH:13][CH:14]=[CH:2][CH:3]=3)[NH:11][C:10]=2[CH2:9][CH2:8]1)[CH2:28][OH:29]Participants
3
Procedure
17 mg of (2S)-2-[[[6,8-dichloro-2,3,4,9-tetrahydro-3-(3-phenylpropyl)-1H-carbazol-3-yl]methyl]amino]-3-methyl-1-butanol 286 is produced analogously with use of 2,4-dichlorophenylhydrazine.
Sources & evidence
- ORD record
- ord-ee57eb0d73f3452494df84f901343f05
- Source dataset
- uspto-grants-2006_10
- Patent number
- US07122570B2
Reaction notes
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