Nitroxyl → 2-Octanone

Participants

Reaction Steps

In a flask 0.072 g (0.05 mmol) of the product from example 1, 2.5 g (19.2 mmol) of 2-octanol and 10 ml of dichloromethane and 2.8 gr of KHCO3 (20% sol.) were added; the heterogeneous mixture was cooled to 10–15° C. then was dropped 13.8 g of an aqueous solution of NaOCl (10.5%). After 3 hours the crude organic layer was analyzed using GC: 98.6% of 2-octanone was obtained as desired product.

Provenance & Evidence