Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | m-Toluidine | HCID 7934 | — |
| Reactant | HCID 178494824 | HCID 178494824 | — |
| Product | HCID 178494825 | HCID 178494825 | 81% |
Reaction Steps
A suspension of 8-bromo-2-(2-methoxy-ethyl)-6-morpholin-4-yl-9H-purine (0.42 g, 1.2 mmol) in m-toluidine (0.5 mL, 3.8 eq) in a tightly stoppered flask was heated at 190° C. for 15 minutes. Column chromatography afforded [2-(2-methoxy-ethyl)-6-morpholin-4-yl-9H-purin-8-yl]-m-tolyl-amine (0.36 g, 81%) as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07122665B2 |
|---|
| Source dataset | uspto-grants-2006_10 |
|---|
| ORD ID | ord-ab45d7bf34044a63b7dbdfcfa4e40e00 |
|---|
| Source note | uspto-grants-2006_10 |
|---|
