Cyclohexanone → HCID 58718605, compound

HRID 1244853Notes

Reaction equation

HRID 1244853 reaction equation
[NH2:1][C@H:2]1[CH2:6][CH2:5][N:4]([C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8])[CH2:3]1.[C:14]1(=O)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:14]1([NH:1][C@H:2]2[CH2:6][CH2:5][N:4]([C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8])[CH2:3]2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 7967CyclohexanoneHCID 854071tert-butyl (3S)-3-aminopyrrolidine-1-carboxylate

Product 1

HCID 58718605HCID 58718605, compound

Procedure

tert-butyl (3S)-3-(cyclohexylamino)pyrrolidine-1-carboxylate was prepared by a method similar to that described in preparation 1 using tert-butyl (3S)-3-aminopyrrolidine-1-carboxylate and cyclohexanone to yield the desired product, 5.9 g (82%).

Workup

  1. customtert-butyl (3S)-3-(cyclohexylamino)pyrrolidine-1-carboxylate was prepared by a method similar to

Sources & evidence

ORD record
ord-de7fd1632c2d4c2ca44e13bdb0e429e4
Source dataset
uspto-grants-2006_10
Patent number
US07122683B2

Reaction notes

Loading…