Benzyl Bromide → HCID 21919169, compound

Participants

Reaction Steps

4-(3,4,5,6-Tetramethoxy-2-methylbenzyl)-2-hydroxybenzaldehyde (743 mg, 2.14 mmol) was dissolved in acetone (50 ml) and, after addition of anhydrous sodium carbonate (593 mg, 4.30 mmol) and benzyl bromide (477 mg, 2.79 mmol), the mixture was stirred at room temperature for 16 hours. The reaction solution was filtered and the residue obtained by concentration of the filtrate was purified by silica gel column chromatography (hexane:ethyl acetate=3:1) to give the title compound (864 mg, 1.98 mmol, 93%).

Provenance & Evidence