HCID 21919196, compound → HCID 21919163, compound

HRID 1245163Notes

Reaction equation

HRID 1245163 reaction equation
[CH3:1][O:2][C:3]1[C:4]([CH3:34])=[C:5]([C:25]([O:32][CH3:33])=[C:26]([O:30][CH3:31])[C:27]=1[O:28][CH3:29])[CH2:6][C:7]1[CH:8]=[CH:9][C:10]([O:17]CC2C=CC=CC=2)=[C:11]([CH:16]=1)[C:12]([O:14][CH3:15])=[O:13].[H][H]>CO.[C].[Pd]>[CH3:1][O:2][C:3]1[C:4]([CH3:34])=[C:5]([C:25]([O:32][CH3:33])=[C:26]([O:30][CH3:31])[C:27]=1[O:28][CH3:29])[CH2:6][C:7]1[CH:8]=[CH:9][C:10]([OH:17])=[C:11]([CH:16]=1)[C:12]([O:14][CH3:15])=[O:13]

Participants

5

Reactant 2

HCID 21919196HCID 21919196, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21919163HCID 21919163, compoundYield 92.5%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 887MethanolSolvent

Procedure

Methyl 5-(3,4,5,6-tetramethoxy-2-methylbenzyl)-2-benzyloxybenzoate (15.0 g, 32.1459 mmol) was dissolved in methanol (200 ml), added to a methanolic suspension (200 ml) of 10% palladium-carbon (1.0 g) and stirred for 16 hours at room temperature in a hydrogen atmosphere. The reaction solution was filtered and the filtrate was concentrated under reduced pressure to give the title compound (11.2 g, 29.7340 mmol, 92%).

Workup

  1. filtrationThe reaction solution was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-f518de0706fc49088704c2fa71b51d58
Source dataset
uspto-grants-2006_10
Patent number
US07122543B2

Reaction notes

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