HCID 21919132, compound → 5-(3,4,5,6-Tetramethoxy-2-methylbenzyl)-2-(3-methoxyphenyl)benzoic acid

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Reaction Steps

Methyl 5-(3,4,5,6-tetramethoxy-2-methylbenzyl)-2-(3-methoxyphenyl)benzoate (1.23 g, 2.6394 mmol) was dissolved in a mixed solution of a 1N aqueous solution of sodium hydroxide (20 ml) and 1,4-dioxane (40 ml) followed by stirring at room temperature for 16 hours. The reaction solution was diluted with water (200 ml), washed with ether, acidified with concentrated hydrochloric acid and extracted with ether. The extract was washed with water and dried and the solvent was evaporated therefrom to give the title compound (1.03 g, 2.2787 mmol, 85%).

Provenance & Evidence