HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+-)-alpha-Methyl-alpha-phenylsuccinimide → 3-Methyl-3-phenyl-1-(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)pyrrolidine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+-)-alpha-Methyl-alpha-phenylsuccinimide | HCID 92154 | — |
| Reactant | 3-Trifluoromethyl-7-propyl-6-(3-bromopropyloxy)-benzisoxazole | HCID 12031259 | — |
| Product | 3-Methyl-3-phenyl-1-(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)pyrrolidine-2,5-dione | HCID 10254304 | — |
Reaction Steps
3-Methyl-3-phenyl-1-(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)pyrrolidine-2,5-dione was prepared as for Example 10 from 3-methyl-3-phenylpyrrolidine-2,5-dione and the bromide from Example 7. After aqueous work-up and silica gel chromatography, the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07125865B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-4237334ff2ed4b2284cbaa212a983f1d |
| Source note | uspto-grants-2006_10 |