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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1245315Generated: November 2, 2026

Hydantoin → 3-(3-{[7-Propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)imidazolidine-2,4-dione

https://huagongshe.com/reaction/1245315

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydantoinHCID 10006—
Reactant3-Trifluoromethyl-7-propyl-6-(3-bromopropyloxy)-benzisoxazoleHCID 12031259—
SolventDiethyl EtherHCID 3283—
Product3-(3-{[7-Propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)imidazolidine-2,4-dioneHCID 21911008—

Reaction Steps

3-(3-{[7-Propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)imidazolidine-2,4-dione was prepared as for Example 10 from imidazolidine-2,4-dione and the bromide from Example 7. After aqueous ether work-up and silica gel chromatography, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125865B2
Source datasetuspto-grants-2006_10
ORD IDord-70b3586fb4ac45948ce61f882407fe20
Source noteuspto-grants-2006_10