HRID1245321

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID259

Bromide

Br-

2 次

HCID93043

5-Methyl-5-phenylhydantoin

C10H10N2O2

HCID21910983

未命名化合物

HCID135800811

未命名化合物

PRODUCTS

生成物

结构：CCCc1c(OCCCN2C(=O)NC(C)(c3ccccc3)C2=O)ccc2c(-c3ccccc3)noc12

HCID21910997

未命名化合物

PROCEDURE

实验过程

rac-5-Methyl-5-phenyl-3-(3-{[7-propyl-3-(phenyl)-1,2-benzisoxazol-6-yl]oxy}propyl)imidazolidine-2,4-dione was prepared as for Example 10 from 5-methyl-5-phenylimidazolidine-2,4-dione and the appropriate bromide. The bromide, 7-propyl-3-phenyl-6-(3-bromopropyloxy)-1,2-benzisoxazole, was prepared as for Example 7 using the 7-propyl-3-phenyl-6-hydroxy-1,2-benzisoxazole prepared in Example 6.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3bb7a04299de480087d56592438910b2
来源数据集: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07125865B2
来源说明: uspto-grants-2006_10

反应 SMILES

[CH3:1][C:2]1([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[NH:6][C:5](=[O:7])[NH:4][C:3]1=[O:8].[Br-].[CH2:16]([C:19]1[C:27]2[O:26][N:25]=[C:24]([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)[C:23]=2[CH:22]=[CH:21][C:20]=1[O:34][CH2:35][CH2:36][CH2:37]Br)[CH2:17][CH3:18].C(C1C2ON=C(C3C=CC=CC=3)C=2C=CC=1O)CC>>[CH3:1][C:2]1([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)[NH:6][C:5](=[O:7])[N:4]([CH2:37][CH2:36][CH2:35][O:34][C:20]2[CH:21]=[CH:22][C:23]3[C:24]([C:28]4[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=4)=[N:25][O:26][C:27]=3[C:19]=2[CH2:16][CH2:17][CH3:18])[C:3]1=[O:8]