2,5-Piperidinedione → 1-(3-{[7-Propyl-3-(phenyl)-1,2-benzisoxazol-6-yl]oxy}propyl)piperidin-2,5-dione

Participants

Role	Name	HCID	Charge
Reactant	2,5-Piperidinedione	HCID 533930	—
Reactant	Rac-5-methyl-5-phenyl-3-(3-{[7-propyl-3-(phenyl)-1,2-benzisoxazol-6-yl]oxy}propyl)imidazolidine-2,4-dione	HCID 21910997	—
Product	1-(3-{[7-Propyl-3-(phenyl)-1,2-benzisoxazol-6-yl]oxy}propyl)piperidin-2,5-dione	HCID 10409063	—

Reaction Steps

1-(3-{[7-Propyl-3-(phenyl)-1,2-benzisoxazol-6-yl]oxy}propyl)piperidin-2,5-dione was prepared as for Example 10 from piperidin-2,5-dione and the bromide from Example 27. After aqueous work-up and silica gel chromatography, the title compound was obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07125865B2
Source dataset	uspto-grants-2006_10
ORD ID	ord-c9e675fdf03e4540b1f1a1736615f414
Source note	uspto-grants-2006_10