HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(tert-Butyl)pyridin-2-amine → 1-(t-Butoxycarbonyl)-4-(7-t-butylimidazo[1,2-a]pyridin-3-yl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(tert-Butyl)pyridin-2-amine | HCID 12351941 | — |
| Reactant | 1-t-Butyloxycarbonyl-4-(1-bromo-formylmethyl)piperidine | HCID 18461140 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(t-Butoxycarbonyl)-4-(7-t-butylimidazo[1,2-a]pyridin-3-yl)piperidine | HCID 21912757 | — |
Reaction Steps
The title compound was prepared from 470 mg of 1-t-butyloxycarbonyl-4-(1-bromo-formylmethyl)piperidine (from Piperidine 1, Step C) and 277 mg of 2-amino-4-tert-butyl pyridine (from Step A) in 12 mL ethanol using a procedure analogous to that described in Piperidine 1, Step D to provide the title compound as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07125887B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-d72eae05fda8423cbfb2b9e1ae64bd0f |
| Source note | uspto-grants-2006_10 |