HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminopyridine → 2-Ethylimidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminopyridine | HCID 10439 | — |
| Reactant | 1-Bromo-2-butanone | HCID 13156 | — |
| Reactant | 1-t-Butyloxycarbonyl-4-(1-bromo-formylmethyl)piperidine | HCID 18461140 | — |
| Product | 2-Ethylimidazo[1,2-a]pyridine | HCID 21831991 | — |
Reaction Steps
The title compound was prepared from 2-aminopyridine and 1-bromo-2-butanone, employing procedures analogous to those described for Piperidine 1. 1H NMR (500 MHz, CDCl3) δ 1.34 (t, J=7.3 Hz, 3H), 2.82 (q, J=7.6 Hz, 2H), 6.70 (t, J=6.6 Hz, 1H), 7.10 (m, 1H), 7.32 (s, 3H), 7.51 (d, J=8.9 Hz, 1H), 8.03 (dd, J=6.6, 0.9 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07125887B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-9f493c7dd14d4f50bcec6bf170509ef8 |
| Source note | uspto-grants-2006_10 |