Piperidine → HCID 69665796, compound

Participants

Reaction Steps

The title compound was prepared from 1-tert-butoxycarbonyl-3-(R)-(1-(R)-(4-(1,3-diethyl-5-methylpyrazol-4-yl)piperidin-1-yl)ethyl)-4-(S)-(3-fluorophenyl)pyrrolidine (from Step E) using a procedure analogous to that described for Piperidine 8, Step F. 1H NMR (500 MHz) δ 0.94 (d, J=6.4, 3H), 1.08 (m, 1H), 1.19 (t, J=7.5, 3H), 1.35 (t, J=7.2, 3H), 1.56 (m, 1H), 1.79 (m, 1H), 1.92 (m, 1H), 2.10–2.25 (m, 5H), 2.33 (m, 1H), 2.45–2.88 (m, 8H), 3.19–3.39 (m, 3H), 4.01 (q, J=7.2, 2H), 6.83 (m, 1H), 7.04 (m, 1H), 7.10 (m, 1H), 7.22 (m, 1H).

Provenance & Evidence