HCID 208188, compound → HCID 9902734, compound

HRID 1245634Notes

Reaction equation

HRID 1245634 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([NH2:10])[S:5][C:6]=1[CH2:7][CH2:8][CH3:9].[Cl:11][C:12]1[C:13]([CH3:22])=[C:14]([S:18](Cl)(=[O:20])=[O:19])[CH:15]=[CH:16][CH:17]=1>>[Cl:11][C:12]1[C:13]([CH3:22])=[C:14]([S:18]([NH:10][C:4]2[S:5][C:6]([CH2:7][CH2:8][CH3:9])=[C:2]([CH3:1])[N:3]=2)(=[O:20])=[O:19])[CH:15]=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 208188HCID 208188, compoundHCID 5227343-Chloro-2-methylbenzenesulfonyl chloride

Product 1

HCID 9902734HCID 9902734, compoundYield 46%

Procedure

The title compound was prepared from 4-methyl-5-propyl-1,3-thiazol-2-ylamine (METHOD I) and 3-chloro-2-methylbenzenesulfonyl chloride according to METHOD A, yellow solid, 110 mg (46% yield): HRMS Calcd (found) for C14H17ClN2O2S2 m/z 344.0420 (344.0403).

Sources & evidence

ORD record
ord-5359960267834bcd89805719bd2dcd56
Source dataset
uspto-grants-2006_10
Patent number
US07125900B2

Reaction notes

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