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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1245638Generated: October 26, 2026

3-Chloro-2-methylbenzenesulfonyl chloride → 3-Chloro-N-(4-isopropyl-1,3-thiazol-2-yl)-2-methylbenzenesulfonamide

https://huagongshe.com/reaction/1245638

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-2-methylbenzenesulfonyl chlorideHCID 522734—
Reactant4-(Propan-2-yl)-1,3-thiazol-2-amineHCID 7064077—
Product3-Chloro-N-(4-isopropyl-1,3-thiazol-2-yl)-2-methylbenzenesulfonamideHCID 988061348%

Reaction Steps

The title compound was prepared from 4-isopropyl-1,3-thiazol-2-ylamine (METHOD I) and 3-chloro-2-methylbenzenesulfonyl chloride according to METHOD A, white foam, 80 mg (48% yield): HRMS Calcd (found) for C13H15ClN2O2S2 m/z 330.0263 (330.0257).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125900B2
Source datasetuspto-grants-2006_10
ORD IDord-a282b427c4a54840918a7a9a05643bf6
Source noteuspto-grants-2006_10