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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1245639Generated: October 25, 2026

3-Chloro-2-methylbenzenesulfonyl chloride → N-(4-Butyl-1,3-thiazol-2-yl)-3-chloro-2-methylbenzenesulfonamide

https://huagongshe.com/reaction/1245639

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-2-methylbenzenesulfonyl chlorideHCID 522734—
Reactant4-Butyl-1,3-thiazol-2-amineHCID 10487124—
ProductN-(4-Butyl-1,3-thiazol-2-yl)-3-chloro-2-methylbenzenesulfonamideHCID 1026905822%

Reaction Steps

The title compound was prepared from 4-butyl-1,3-thiazol-2-ylamine (METHOD H) and 3-chloro-2-methylbenzenesulfonyl chloride according to METHOD A, yellow solid, 52 mg (22% yield): HRMS Calcd (found) for C14H17ClN2O2S2 m/z 344.0420 (334.0414).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125900B2
Source datasetuspto-grants-2006_10
ORD IDord-91d9d7edf35e4796917fccc7089b170c
Source noteuspto-grants-2006_10