HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 3,6-dimethyl-4-N-(pentan-3-yl)-2-N-(2,4,6-trimethylphenyl)pyridine-2,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 4-(1-Ethyl-propylamino)-6-methyl-2-(2,4,6-trimethyl-phenylamino)-nicotinic acid | HCID 24806259 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | 3,6-dimethyl-4-N-(pentan-3-yl)-2-N-(2,4,6-trimethylphenyl)pyridine-2,4-diamine | HCID 21912204 | — |
Reaction Steps
The title compound was prepared by reduction of 4-(1-ethyl-propylamino)-6-methyl-2-(2,4,6-trimethyl-phenylamino)-nicotinic acid with 1M of lithium aluminium hydride in diethyl ether and aluminium trichloride at reflux. 1H NMR(CDCl3) 6.9(s,2H), 6.0(s,1H), 5.4(brs,1H), 3.6(d,1H), 3.3(m,1H), 2.32(s,3H), 2.2(s,3H), 2.15(s,6H), 1.4–1.7(m,4H), 1.0(t,6H) ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07125880B1 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-783aab045169466ab7eb48f8bf7abbea |
| Source note | uspto-grants-2006_10 |