4-Hydroxyphenylacetone → 4-[2-(2,2,6,6-Tetramethylpiperidin-1-yl)ethoxy]phenyl acetone

HRID 1245781Notes

Reaction equation

[CH3:1][C:2]1([CH3:13])[CH2:7][CH2:6][CH2:5][C:4]([CH3:9])([CH3:8])[N:3]1[CH2:10][CH2:11]Cl.[OH:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][C:22](=[O:24])[CH3:23])=[CH:17][CH:16]=1>>[CH3:1][C:2]1([CH3:13])[CH2:7][CH2:6][CH2:5][C:4]([CH3:9])([CH3:8])[N:3]1[CH2:10][CH2:11][O:14][C:15]1[CH:16]=[CH:17][C:18]([CH2:21][C:22](=[O:24])[CH3:23])=[CH:19][CH:20]=1

Participants

Reactant 2

HCID 70192744-Hydroxyphenylacetone

HCID 141262461-(2-Chloroethyl)-2,2,6,6-tetramethylpiperidine

Product 1

HCID 219145004-[2-(2,2,6,6-Tetramethylpiperidin-1-yl)ethoxy]phenyl acetone

Procedure

Prepared from 2-(2,2,6,6-tetramethylpiperidin-1-yl)ethyl chloride and 4-hydroxyphenylacetone in a similar manner to Example 2 (b).

Sources & evidence

ORD record: ord-f2b14b61230a4628986f8741f3bb82bf
Source dataset: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07125896B2

Reaction notes

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