4-Hydroxyphenylacetone → 4-[(1,2,5-Thiadiazol-3-yl)methoxy]phenyl acetone

HRID 1245783Notes

Reaction equation

Br[CH2:2][C:3]1[CH:7]=[N:6][S:5][N:4]=1.[OH:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][C:16](=[O:18])[CH3:17])=[CH:11][CH:10]=1>>[S:5]1[N:6]=[CH:7][C:3]([CH2:2][O:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15][C:16](=[O:18])[CH3:17])=[CH:13][CH:14]=2)=[N:4]1

Participants

Reactant 2

HCID 70192744-Hydroxyphenylacetone

HCID 133468803-(Bromomethyl)-1,2,5-thiadiazole

Product 1

HCID 219142814-[(1,2,5-Thiadiazol-3-yl)methoxy]phenyl acetone

Procedure

Prepared from 3-bromomethyl-1,2,5-thiadiazole and 4-hydroxyphenylacetone by the method of Example 1.

Sources & evidence

ORD record: ord-6cb9ede3ab484b7a86f49abefbfb5a58
Source dataset: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07125896B2

Reaction notes

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