2-(Chloromethyl)-1-methylpiperidine → HCID 21914454, compound

HRID 1245784Notes

Reaction equation

[CH3:1][N:2]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]1[CH2:8]Cl.[OH:10][C:11]1[CH:16]=[CH:15][C:14]([CH2:17][C:18](=[O:20])[CH3:19])=[CH:13][CH:12]=1>>[CH3:1][N:2]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]1[CH2:8][O:10][C:11]1[CH:12]=[CH:13][C:14]([CH2:17][C:18](=[O:20])[CH3:19])=[CH:15][CH:16]=1

Participants

Reactant 2

HCID 1235172-(Chloromethyl)-1-methylpiperidine

HCID 70192744-Hydroxyphenylacetone

Product 1

HCID 21914454HCID 21914454, compound

Procedure

Prepared from 1-methyl-2-chloromethylpiperidine and 4-hydroxyphenylacetone by the method of Example 1 to give a mixture (50:50) of the above product and 4-([1-methyl-piperidin-2-yl]methoxy)phenyl acetone.

Sources & evidence

ORD record: ord-89f6b7a9784444f08c118445d4875bc7
Source dataset: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07125896B2

Reaction notes

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