2,5-Dibromopyridine → tert-Butyl 4-((5-bromopyridin-2-yl)oxy)piperidine-1-carboxylate

HRID 1245798Notes

Reaction equation

HRID 1245798 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[C:9]([O:13][C:14]([N:16]1[CH2:21][CH2:20][CH:19]([OH:22])[CH2:18][CH2:17]1)=[O:15])([CH3:12])([CH3:11])[CH3:10]>>[C:9]([O:13][C:14]([N:16]1[CH2:21][CH2:20][CH:19]([O:22][C:2]2[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=2)[CH2:18][CH2:17]1)=[O:15])([CH3:12])([CH3:10])[CH3:11]

Participants

3

Reactant 2

HCID 693532,5-DibromopyridineHCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Product 1

HCID 21914479tert-Butyl 4-((5-bromopyridin-2-yl)oxy)piperidine-1-carboxylate

Procedure

Prepared from 2,5-dibromopyridine and 1-t-butyloxycarbonylpiperidin-4-ol by the method of Example 10 (b).

Sources & evidence

ORD record
ord-a2e8b1c259da4af499eb0dfe57868932
Source dataset
uspto-grants-2006_10
Patent number
US07125896B2

Reaction notes

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