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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1245929Generated: October 30, 2026

4-Morpholinecarbonyl chloride → N-{2-[2-(4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl)ethoxy]ethyl}morpholine-4-carboxamide

https://huagongshe.com/reaction/1245929

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Morpholinecarbonyl chlorideHCID 84810—
Reactant1-[2-(2-aminoethoxy)ethyl]-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amineHCID 21913053—
ProductN-{2-[2-(4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl)ethoxy]ethyl}morpholine-4-carboxamideHCID 10022418—

Reaction Steps

Using the method of Examples 54–68, 4-morpholinecarbonyl chloride was reacted with 1-[2-(2-aminoethoxy)ethyl]-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The product was purified using Method A. The observed accurate mass was 377.2295.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125890B2
Source datasetuspto-grants-2006_10
ORD IDord-0dce8f1573914a2c90818a9eb4d3619f
Source noteuspto-grants-2006_10