HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chlorooxindole → 5-(5-Chloro-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-4-methyl-1H-pyrrole-2-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chlorooxindole | HCID 152801 | — |
| Reactant | Ethyl 5-formyl-4-methyl-1H-pyrrole-2-carboxylate | HCID 9855648 | — |
| Product | 5-(5-Chloro-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-4-methyl-1H-pyrrole-2-carboxylic acid ethyl ester | HCID 67281073 | 94% |
Reaction Steps
5-Chloro-1,3-dihydroindol-2-one (2.22 g, 13.2 mmol) was condensed with 5-formyl-4-methyl-1H-pyrrole-2-carboxylic acid ethyl ester (2.43 g) using method E to give 4.1 g (94%) of the title compound as an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07125905B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-b0167678838b4dd4b9b44a7dd79c379e |
| Source note | uspto-grants-2006_10 |