HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-oxindole → 5-(5-Bromo-2-oxo-1,2-Dihydroindol-3-Ylidenemethyl)-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid (3-Imidazol-1-yl-Propyl)Amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-oxindole | HCID 611193 | — |
| Reactant | 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-imidazol-1-ylpropyl)amide | HCID 86586208 | — |
| Product | 5-(5-Bromo-2-oxo-1,2-Dihydroindol-3-Ylidenemethyl)-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid (3-Imidazol-1-yl-Propyl)Amide | HCID 67280211 | 59% |
Reaction Steps
5-Bromo-1,3-dihydroindol-2-one (0.09 g, 0.4 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-imidazol-1-ylpropyl)amide (0.1 g) to give 0.1 g (59%) of the title compound as an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07125905B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-2bfc2f1d03c0467488f838050af434a1 |
| Source note | uspto-grants-2006_10 |