HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Phenyloxindole → 2,4-Dimethyl-5-(2-oxo-5-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Phenyloxindole | HCID 13301978 | — |
| Reactant | N-(2-(diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide | HCID 20761785 | — |
| Product | 2,4-Dimethyl-5-(2-oxo-5-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide | HCID 67280956 | 46% |
Reaction Steps
5-Phenyl-1,3-dihydroindol-2-one (80 mg, 0.4 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide (0.1 g) using method B to give 79 mg (46%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07125905B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-df07d7749d5342e28d035d61ad8625e5 |
| Source note | uspto-grants-2006_10 |