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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1246129Generated: October 26, 2026

5-Phenyloxindole → 2,4-Dimethyl-5-(2-oxo-5-Phenyl-1,2-Dihydroindol-3-Ylidenemethyl)-1H-Pyrrole-3-Carboxylic Acid (3-Imidazol-1-Ylpropyl) Amide

https://huagongshe.com/reaction/1246129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-PhenyloxindoleHCID 13301978—
ReactantHCID 86586208HCID 86586208—
Product2,4-Dimethyl-5-(2-oxo-5-Phenyl-1,2-Dihydroindol-3-Ylidenemethyl)-1H-Pyrrole-3-Carboxylic Acid (3-Imidazol-1-Ylpropyl) AmideHCID 6728260659%

Reaction Steps

5-Phenyl-1,3-dihydroindol-2-one (8 mg, 0.04 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-imidazol-1-ylpropyl)amide (10 mg) to give 10 mg (59%) of the title compound as an orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125905B2
Source datasetuspto-grants-2006_10
ORD IDord-319c364ba187498ab55a0286a987c264
Source noteuspto-grants-2006_10