反应详情

In a 100 ml round-bottomed flask, 1 eq. of the compound obtained in Step B is dissolved in 20 ml of CCl4. 1 eq. of N-bromosuccinimide and 0.04 eq. of benzoyl peroxide are then added, and the mixture is irradiated by means of a halogen lamp and maintained at reflux for 4 hours. At the end of the reaction, the insoluble material is filtered off, and the carbon tetrachloride is evaporated off. The residue obtained is purified by chromatography on a silica gel column.

1. customthe mixture is irradiated by means of a halogen lamp
2. temperaturemaintained
3. temperatureat reflux for 4 hours
4. customAt the end of the reaction
5. filtrationthe insoluble material is filtered off
6. customthe carbon tetrachloride is evaporated off
7. customThe residue obtained
8. customis purified by chromatography on a silica gel column