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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1246427Generated: October 30, 2026

HCID 21914748, compound → HCID 21915094, compound

https://huagongshe.com/reaction/1246427

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21914748HCID 21914748—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 21915094HCID 2191509471.4%

Reaction Steps

A mixture of N-{4-[(E)-2-(4-nitrophenyl)ethenyl]-1,3-thiazol-2-yl}acetamide (250 mg), palladium on carbon (25 mg) and methanol (2.5 ml) was stirred under hydrogen atmosphere for 2 hours at ambient temperature. The catalyst was filtered off and the filtrate was concentrated in vacuo. The crystalline residue was collected and washed with isopropyl ether to give N-{4-[(E)-2-(4-aminophenyl)ethenyl]-1,3-thiazol-2-yl}acetamide (160 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125901B2
Source datasetuspto-grants-2006_10
ORD IDord-b389b520922a4ebdb2a483ac7eaa0fdd
Source noteuspto-grants-2006_10