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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1246474Generated: October 30, 2026

HCID 21914760, compound → Carbamic acid, [4-[2-(4-aminophenyl)ethyl]-2-thiazolyl]-, phenylmethyl ester

https://huagongshe.com/reaction/1246474

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21914760HCID 21914760—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductCarbamic acid, [4-[2-(4-aminophenyl)ethyl]-2-thiazolyl]-, phenylmethyl esterHCID 2191480592.5%

Reaction Steps

A mixture of benzyl 4-[(E)-2-(4-nitrophenyl)ethenyl]-1,3-thiazol-2-ylcarbamate (1.4 g), palladium on carbon (140 mg) and methanol (2 ml) was stirred under hydrogen atmosphere (4 atm) at ambient temperature for 8 hours. The catalyst was filtered off, and the filtrate was concentrated in vacuo to give benzyl 4-[2-(4-aminophenyl)ethyl]-1,3-thiazol-2-ylcarbamate (1.2 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125901B2
Source datasetuspto-grants-2006_10
ORD IDord-817b6b3b2557453da2b8c232a93c2968
Source noteuspto-grants-2006_10