HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21914760, compound → Carbamic acid, [4-[2-(4-aminophenyl)ethyl]-2-thiazolyl]-, phenylmethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21914760 | HCID 21914760 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Carbamic acid, [4-[2-(4-aminophenyl)ethyl]-2-thiazolyl]-, phenylmethyl ester | HCID 21914805 | 92.5% |
Reaction Steps
A mixture of benzyl 4-[(E)-2-(4-nitrophenyl)ethenyl]-1,3-thiazol-2-ylcarbamate (1.4 g), palladium on carbon (140 mg) and methanol (2 ml) was stirred under hydrogen atmosphere (4 atm) at ambient temperature for 8 hours. The catalyst was filtered off, and the filtrate was concentrated in vacuo to give benzyl 4-[2-(4-aminophenyl)ethyl]-1,3-thiazol-2-ylcarbamate (1.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07125901B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-817b6b3b2557453da2b8c232a93c2968 |
| Source note | uspto-grants-2006_10 |