HCID 69223904, compound → HCID 21914742, compound

Participants

Reaction Steps

Methyl (2E)-3-[3-(methylsulfonyl)phenyl]acrylate (600 mg), MeOH (6.ml) and then 10% palladium carbon (99.9 mg) were combined under N2 atmosphere. The reaction mixture was stirred at r.t. for 7 hours under H2 atmosphere (1 atm), and filtered through a celite pad. The filtrate was concentrated in vacuo. The residue was purified by flash column chromatography over silica gel with n-hexane/AcOEt (1:1→1:2) as an eluent to give methyl 3-[3-(methylsulfonyl)phenyl]propanoate (283.3 mg) as colorless oil.

Provenance & Evidence