HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → (3,5,5 Trimethyl hexyl) 4-aminobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Benzocaine | HCID 2337 | — |
| Reactant | 3,5,5-Trimethyl-1-hexanol | HCID 18938 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Solvent | Cyclohexane | HCID 8078 | — |
| Product | (3,5,5 Trimethyl hexyl) 4-aminobenzoate | HCID 69639835 | — |
Reaction Steps
Sodium metal (1 g cat.) was added to ethanol (30 mL) to give a solution which was added to a suspension of ethyl 4-aminobenzoate (175 g, 1.06 mol) and 3,5,5 trimethyl hexanol (200 g, 1.4 mol) in cyclohexane (300 mL). The suspension was heated under reflux for 24 hours with the azeotropic removal of ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129204B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-74ff96502e7f4c339282b0b43bcc57c1 |
| Source note | uspto-grants-2006_10 |