Ethanol → HCID 21904092, compound

Participants

Reaction Steps

Sodium methoxide (2.5 g, cat.) was added to a suspension of ethyl 4-aminobenzoate (10 g, 60 mmol), citronellol (15 g, 90 mmol) in cyclohexane (100 mL). The suspension was heated under reflux for 8 hours with the azeotropic removal of EtOH. The mixture was cooled and filtered through a plug of silica (400 mL) with cyclohexane:isopropanol (95:5) as eluant to give the ester (5.0 g, 30%)as a pale yellow solid.

Provenance & Evidence